I never had any coil whine issues with my PC but I just started F@H recently (only with GPU) and whenever its folding, I hear coil whine whenever I move my mouse. I don't get that with any other workload I've done over the years. I just find it interesting.

And the coil whine is ONLY tied to the mouse movement. It wont trigger with anything else like typing on a keyboard or watching video while folding.