I use a Razer Mamba and I don't notice any input lag while in wireless mode. I also love the convenience of a wireless mouse and not having to deal with a cord. The only issue is sometimes my macro profiles don't auto switch, or take a really long time, when I start a game. ie. I set the DPI up/down buttons to gadgets in BF3 and I don't check the mouse profile before I start playing, then I die cause I can't drop a med-pack. :( In wired mode, there are no problems at all. I hope this helps.