LED_Guy

You're missing the opportunity for an ultimate sleeper.  Those old Commodore PET computers in the background!!!!
 
GO FOR IT ! ! !

No, my point is that you only slammed Seasonic,  You didn’t back up your criticisms, but worse you didn’t offer an alternative.
 
”I’ve heard there are issues with some Seasonic PSUs, have you looked into xxxx or yyy, I’ve heard good things about them . . .”
That’s useful information.  If you’re not going to offer a suggestion you’re just bitching, so what’s your beef with Seasonic?  You prefer ?????
 
The 4+ years of experience with two HEDT builds (60+ hrs/week) without a problem is a testimony to quality. 

I dont think you are going to be able to get 256GB DDR4 Running at 3600 mhz. Goodluck with that  
 
I would say you should get a 1000W PSU with all the hardware in the system you are using. Although i dont know if its a great time to buy a 3970x with the potential for 5000 series Threadripper.

I'd guess you'll be fine with an A tier 850W unit -- RMx, Seasonic Focus GX/PX, etc and above are all in this category.
 
For comparison, a 3970X is pretty comparable to an overclocked 10900K in power consumption, so you don't need anything super-crazy by modern standards, even though it's a HEDT platform.

I'm going to save you tons of money: solidworks doesn't require quadro for GPU acceleration: THEY RECOMMEND IT.

RTX 3080 or 3090 is cheaper and more powerful, but some of my work involves SOLIDWORKS which requires a Quadro for GPU acceleration.  In an ideal world it wouldn’t matter, so I’m stuck paying a premium for the Quadra.  For the cost of the 6000 (and its 4,608 CUDA cores), I could put in dual 3090’s and have just under 21,000 CUDA cores!

The Long Boi.
Not really - but had to bring it somewhere

SolidWorks (CAD) and Flow (CFD) won't play with an RTX 3090.  It's Quadro or run everything through the CPU.
 
I read the quad RTX 3090 article earlier this evening.  I was shocked at how well everything scaled, but alas that will have to wait for a recreational build.

Comments and suggestions on components other than the mobo, CPU and GPU (Quadro) are welcome.  The GPU(s) will probably be mounted off the mobo using riser cables.
 
This is my inspiration for a custom wall mount system.  I won't rule out a purchased case, but anything that is designed for an EEB mobo tends to be massive.
 

I updated the thread after attending CES.  AMD made an irresistible pitch for switching CPU vendors. 
 
I am open to comments/suggestions on the case.

Comments and suggestions on components other than the mobo, CPU and GPU (Quadro) are welcome.  The GPU(s) will probably be mounted off the mobo using riser cables.
 
This is my inspiration for a custom wall mount system.  I won't rule out a purchased case, but anything that is designed for an EEB mobo tends to be massive.
 

It's been a few years since my last build and time for an upgrade.
Thread updated after attending CES
 
CPU:               Dual Xeon Platinum 8280 Threadripper 3990X
Mobo:             Asus C621E Sage ROG Zenith II Extreme
GPU:               NVidia Quadro RTX 6000 (optional 2nd GPU Nvidia RTX 2080 Ti)
RAM:               256GB DDR4  (Nemix 3200 MHz ECC)
PSU:                Seasonic Prime Ultra 1000 Titanium Corsair HX1200i
Boot:               1TB Samsing 970 Pro 2x 512GB Samsung 980 Pro (if available in time)
Data:               2x 2TB Samsung 860 Evo
Cooling:         TBD
WiFi:               TBD
Case:              Custom wall mount wood or ?????? InWin 925
NAS:               4x4TB WD black My Cloud (RAID 1)
 
This is primarily for work.  I do ray trace optical design.  Unfortunately the software doesn't take advantage of GPU acceleration.  Depending on complexity, a simulation may require 10's to >100 of GB of RAM.  Optimization may require hundreds of iterations.
 
I also do thermal management design (CFD/CHT) using SolidWorks and SolidWorks Flow Simulation.  This does take advantage of GPU acceleration, hence the Quadro.
 
I also create custom monte carlo simulations.  I write the software myself and the extreme number of cores and the RAM make it easy (or at least quick).

* thread cleaned *
 
Please keep this on-topic and keep the Community Standards in mind when interacting with others.

i9-9980XE   suggested price = $2000
i9-10980XE suggested price = $1000
 
So for half the price you get something a little faster.  Some sanity is returning to the high end.
 
I will definitely be upgrading this fall.  Compared to a 5960X and 64GB RAM it will be well worth it - I bumping up to at least 128GB RAM!  I do (ray trace) optical design, so the extra cores and RAM will pay off for me big time.

Get a single D5 or a ddc pump. That will be plenty of flow for your needs.

It is much cheaper to do phase change cooling

The clock speed written on the box of a modern Nvidia card is meaningless as they overclock themselves anyway, buy based on cooler quality (which you can't easily change after buying it) rather than rated core clock (which you can easily change).

At 7nm quantum effects start to creep in and your charge carriers (electrons and holes) start to act like waves.  &nm is REALLY small - about 20 atoms!  Look up quantum tunneling.  The little buggers won't stay where they are supposed to.
 
You're resistance for conductors starts to go up dramatically as well.  It becomes increasingly easy to burn out your conductor traces.
 
Your sensitivity to soft errors (bit flip due to background radiation) starts to go up as well.  There is always some natural background radiation, in the materials used to make the chip and from cosmic rays.  Digital ran into problems with this when they were developing their Alpha processor back in the early 1990's.  They characterized the natural radioactive impurites in lead deposits all over the world to identify the mines that produced the "oldest" lead (lead is the end product of radioactive decay for elements with an atomic number >82.  As lead deposits age, more of the natural radioactive impurities have a chance to decay into lead.

Exactly. The space shuttle was just the first in a long line of examples of what happens when politicians get involved in making non administrative flight hardware decisions.

At the moment, I own a pair of 980 HOFs and a pair of 980 Ti HOFs.  I started a build early in the year that got put on hold due to work load.  When I restarted the build, the 980 Ti HOFs were out, so I up-graded.

 
 
I have a CAD model for the 980 HOF - I needed it for planning my build.  I can add in detailed measurements later.  I will be making a model for the 980 Ti HOF as well.

 
 
I found a solution for sag, but it isn't necessarily for the faint of heart.  I haven't done a rendering for the details of the support bracket yet, but let's just say I'm not counting on the mobo for the support.  The distal end supports will include integral cable management trays to route the power cables up and over the back of the cards.

At the moment, I own a pair of 980 HOFs and a pair of 980 Ti HOFs.  I started a build early in the year that got put on hold due to work load.  When I restarted the build, the 980 Ti HOFs were out, so I up-graded.

 
 
I have a CAD model for the 980 HOF - I needed it for planning my build.  I can add in detailed measurements later.  I will be making a model for the 980 Ti HOF as well.

 
 
I found a solution for sag, but it isn't necessarily for the faint of heart.  I haven't done a rendering for the details of the support bracket yet, but let's just say I'm not counting on the mobo for the support.  The distal end supports will include integral cable management trays to route the power cables up and over the back of the cards.

At the moment, I own a pair of 980 HOFs and a pair of 980 Ti HOFs.  I started a build early in the year that got put on hold due to work load.  When I restarted the build, the 980 Ti HOFs were out, so I up-graded.

 
 
I have a CAD model for the 980 HOF - I needed it for planning my build.  I can add in detailed measurements later.  I will be making a model for the 980 Ti HOF as well.

 
 
I found a solution for sag, but it isn't necessarily for the faint of heart.  I haven't done a rendering for the details of the support bracket yet, but let's just say I'm not counting on the mobo for the support.  The distal end supports will include integral cable management trays to route the power cables up and over the back of the cards.

Memory upgrade - I will have 64GB of 3000 MHz CL15 showing up later this week.  Compared to 2800 MHz CL16, that's a 12.5% performance boost.
 
It's not the kind of upgrade most people would really need or notice, but ray tracing is hugely RAM intensive.  This was something I needed.  Fortunately prices have fallen since I started the build and performance has improved.
 
Now I have to sell the "old" DDR4 -

3M makes PCIe x16 extension cables that are about 10" (250 mm) long. They are also shielded so you don't have to worry too much about interferences
Mouser carries them, but they aren't exactly cheap (about $100 ea.). I bought a pair for my build (still in progress)
http://www.mouser.com/ProductDetail/3M-Electronic-Solutions-Division/8KC3-0726-0250/?qs=sA3qAAQcQeGUg2lxOdGD%252bA%3D%3D

I fell in love with the look of the HOFs the moment I saw them.  This build has been in planning for a loooong time.  I was on the waiting list for the 980 HOFs TWICE!  It was a month before I got an email that there were any in inventory.  By the time I could place an order, there was only one left.  A few weeks later I was able to buy my second 980 HOF.
 
My work load went into overdrive late spring/early summer and kept me from doing anything.  Fortunately for me, it means I get to commission my build with 980 Ti HOFs.
 
Water cooling was never really an option or at least consideration.  A lot of the GPU companies put some real effort into the appearance of their cards.  Even the reference NVidia cards look great from the top - IMO.  It always seemed such a waste to hide the artistry and so the tilted installation was born (in my head at least).  Even the Diamond Cooling products for the HOFs just don't hold the same appeal to me.
 
I spent a lot of time looking at different configurations to show off as much of my HOFs as possible.  Once you decide for remote mounting the world really opens up on what you can do.  At one point I was considering mounting the HOFs so one showed the top face and one showed the standard side face, but it just didn't look right AND I had to worry about the exhaust air from one card feeding directly into the fan intakes of the other.  The rendering below gives you an idea of what I am talking about.