When I had FIOS I used MoCA to hook up a wired PC in the basement to the router on the 2nd floor. I used a spare Actiontec MI424 router that I had from my previous house with all the routing features turned off. It worked fine for web browsing and transferring data to/from my server. I've since gotten rid of the PC and do everything over the 5GHz 802.11n or 802.11ac spectrum.
If you don't want to bother with wireless then this is a viable solution. You can also try doing the Powerline thing but depending on your wiring it may not work that well. Keep in mind MoCA and Powerline can have somewhat weird issues but in my experience the MoCA ones were far more straightforward to figure out and fix.
