man, my mom works for a school with really cool smart kids that have "issues," this would be something really cool to share with them, or better yet, build with them. i'd go for the micro-atx.
http://youtu.be/SR9jEczwCZ4?list=UUkWQ0gDrqOCarmUKmppD7GQ this video because it got me into watercooling! and this one:
because i'm asked what the difference is every day, and this helped me explain that better than anyone else!